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研究人才詳細資料


出版年月 著作類別 著作名稱 作者 收錄出處
2019-11 期刊論文 Orabase-formulated gentian violet effectively improved oral potentially malignant disorder in vitro and in vivo Yen-Yun Wang; Ling-Yi Xiao; Pao‐Chu Wu; Yuk‐Kwan Chen; Steven Lo; Stephen Chu‐Sung Hu; Yi-Hua Chen; Charles Chien-Chih Chiu; Shyng-Shiou Yuan* Biochemical Pharmacology
2019-11 研討會論文 A sesterterpene Heteronemin from sponge Hyrtios reticulata induces both apoptotic and ferroptotic deaths in hepatocellular carcinoma cells Pei-Jung Fu, Wen-Tsan Chang2, Mei-Chin Lu3 and Chien-Chih Chiu*
2019-10 期刊論文 Phenoxyphenol Compound 4-HPPP Selectively Induces Antiproliferation Effects and Apoptosis in Human Lung Cancer Cells through Aneupolyploidization and ATR DNA Repair Signaling Wangta Liu, Chang-Yi Wu, Mei-Jei Lu, Yung-Jen Chuang, Eing Mei Tsai, Steve Leu, I-Ling Lin, Chih-Jan Ko*, Chien-Chih Chiu* and Wen-Tsan Chang* Oxidative Medicine and Cellular Longevity
2019-10 研討會論文 Mitochondrial membrane potential and ATP production are diverse in primary cells and cancer cells Wan-Ju Lien1, Bi-Ling Cheng1, Wen-Kuo Hsieh1, Chien-Chih Chiu2,3*, Bin Huang1,3,4*
2019-09 期刊論文 CS-PEI/Beclin-siRNA Downregulate Multidrug Resistance Proteins and Increase Paclitaxel Therapeutic Efficacy against NSCLC Wangta Liu, Yu-Lun Lo, Chin Hsu, Yi-Ting Wu, Zi-Xian Liao, Wen-Jeng Wu, Yi-Jou Chen, Chieh Kao, Chien-Chih Chiu*, and Li-Fang Wang* *Contributed to this work equally. Molecular Therapy — Nucleic Acids
2019-08 期刊論文 Exosomal miR-21 mediates the protective effect of cardiomyocytes-derived conditioned medium on ameliorating myocardial infarction in rats Chen CH, Hsu SY, Chien-Chih Chiu, Leu S* Cells
2019-08 期刊論文 IL-10 from plasmacytoid dendritic cells promotes angiogenesis in the early stage of endometriosis Suen JL1, Chang Y, Shiu YS, Hsu CY, Sharma P, Chien-Chih Chiu, Chen YJ, Hour TC, Tsai EM*
The Journal of Pathology
2019-05 期刊論文 Unfolded Protein Response (UPR) in Survival, Dormancy, Immunosuppression, Metastasis, and Treatments of Cancer Cells Sheng-Kai Hsu†, Chien-Chih Chiu†, Hans-Uwe Dahms, Chon-Kit Chou, Chih-Mei Cheng, Wen-Tsan Chang, Kai-Chun Cheng, Hui-Min David Wang and I-Ling Lin 2*. † Equal contribution. International Journal of Molecular Sciences
2019-04 期刊論文 Inhibitions of melanogenesis via Phyllanthus emblica fruit extract powder in B16F10 cells Yi-Chen Wang, Xing-Yu Haung, Chien-Chih Chiu, Meng-Yi Lin, Wen-Hung Lin, Wen-Tsan Chang, Chung-Chih Tseng, Hui-Min David Wang Food Bioscience
2019-03 期刊論文 Combination therapy of chloroquine and C2-ceramide enhanced cytotoxicity in Lung cancer H460 and H1299 cells Han-Lin Chou, Yi-Hsiung Lin, Wangta Liu, Chang-Yi Wu, Ruei-Nian Li, Hurng-Wern Huang, Chi-Hsien Chou, Shean-Jaw Chiou, Chien Chih Chiu* Cancers
2019-02 期刊論文 Phytochemical Naphtho[1,2-b] furan-4,5-dione Induced Topoisomerase II-mediated DNA Damage Response in Human Non-small-Cell Lung Cancer Ching-Ming Chien, Juan-Cheng Yang, Pin-Hsuan Wu, Chang-Yi Wu, Guan-Yu Chen, Yang-Chang Wu, Chon-Kit Chou, Chih-Hua Tseng, Yeh-Long Chen*, Li-Fang Wang*, Chien-Chih Chiu* Phytomedicine
2019-02 期刊論文 Reduced camptothecin sensitivity of estrogen receptor-positive human breast cancer cells following exposure to di(2-ethylhexyl)phthalate (DEHP) is associated with DNA methylation changes Chon-Kit Chou, Hurng-Wern Huang, Chun-Feng Yang, Hans-Uwe Dahms, Shih-Shin Liang, Tsu-Nai Wang, Po-Lin Kuo, Edward Hsi, Eing-Mei Tsai*, Chien-Chih Chiu* Environmental Toxicology
2018-11 期刊論文 Human non‑small cell lung cancer cells can be sensitized to camptothecin by modulating autophagy Chiu YH, Hsu SH, Hsu HW, Huang KC, Liu W, Wu CY, Huang WP, Chen JY, Chen BH, Chien-Chih Chiu* International of Oncology
2018-11 期刊論文 Protective effects of Lycium barbarum extracts on UVB-induced damage in human retinal pigment epithelial cells accompanied by attenuating ROS and DNA damage Feng-Chi Hsieh, Chun-Tzu Hung, Kai-Chun Cheng, Chang-Yi Wu, Yen-Chun Chen, , and Yu-Jen Wu, Wangta Liu*, Chien-Chih Chiu* Oxidative Medicine and Cellular Longevity
2018-10 期刊論文 Exogenous C8-ceramide induces apoptosis by over-production of ROS and the switch of superoxide dismutases SOD1 to SOD2 in human lung cancer cells Yuli C. Chang, Yao Fong, Eing-Mei Tsai, Ya-Gin Chang, Han Lin Chou, Chang-Yi Wu, Yen-Ni Teng, Ta-Chih Liu, Shyng-Shiou Yuan and Chien-Chih Chiu* International Journal of Molecular Sciences
2018-06 期刊論文 Breast cancer is associated with methylation and expression of a disintegrin and metalloproteinase domain 33 (ADAM33) gene affected by endocrine-disrupting chemicals (EDCs) Pei-Jing Yang, Ming-Feng Hou, Eing-Mei Tsai, Shih-Shin Liang, Chien-Chih Chiu, Fu Ou-Yang, Jung-Yu Kan, Chiung-Yu Peng, Tsu-Nai Wang* Oncology Reports
2018-06 期刊論文 Ethyl acetate extract of Scindapsus cf. hederaceus exerts the inhibitory bioactivity on human non-small cell lung cancer cells through modulating ER stress Chon-Kit Chou, Wangta Liu, Yu-Jie Hong, Hans-Uwe Dahms, Chen-Hao Chiu, Wen-Tsan Chang, Ching-Ming Chien, Chia-Hung Yen, Yuan-Bin Cheng *, Chien-Chih Chiu* International Journal of Molecular Sciences
2018-06 期刊論文 The visceral obesity and cell cycle pathways link the association between bisphenol A exposure and breast cancer Tsu-Nai Wang*, Pei-Jing Yang, Yu-Ting Tseng, Yi-Shan Tsai, Po-Lin Kuo, Chien-Chih Chiu, Shih-Shin Liang, Tsung-Hua Hsieh, Ming-Feng Hou, Eing-Mei Tsai* Oncology Letters
2018-06 研討會論文 Long-term exposure of Phthalate A confers doxorubicin resistance in breast cancer cells through modulating expression of FGF and ABC transporter expression He-Chun Yang, Hurng-Wern Huang, Eing-Mei Tsai*, Chien-Chih Chiu*
2018-05 期刊論文 Effect of bornyl cis-4-hydroxycinnamate on melanoma cell apoptosis is associated with mitochondrial dysfunction and endoplasmic reticulum stress Zih-Yan Yang, Yu-Jen Wu, Chi-I Chang, Chien-Chih Chiu, Mei-Li Wu * International Journal of Molecular Sciences
2018-03 期刊論文 Nuclear factor erythroid-2-related factor regulates LRWD1 expression and cellular adaptation to oxidative stress in human embryonal carcinoma cells Jui-Hsiang Hunga, Shi-Kae Wee, Hany A. Omard, Chia-Hui Su, Hsing-Yi Chen, Pin-Shern Chen, Chien-Chih Chiu, Ming-Syuan Wu, Yen-Ni Teng* Biochimie
2018-02 期刊論文 Resistin facilitates breast cancer progression via TLR4 mediated induction of mesenchymal phenotypes and stemness properties Shyng-shiou Yuan, Chie-Hong Wang, Po-Jen Wang, Ya-Ching Hsieh, Steven Lo, Yi-Chen Lee, Yueh-Chiu Chen, Chun-Hao Tsai, Wen-Chin Chiu, Stephen Hu, Chun-Wun Lu, Yi-Fang Yang, Chien-Chih Chiu, Fu Ou-Yang, Yun-Ming Wang, and Ming-Feng Hou Oncogene
2018-01 期刊論文 A triazole-conjugated benzoxazone induces reactive oxygen species and promotes autophagic apoptosis in human lung cancer cells Chang-Heng Hsieh, Jing-Ping Wang, Chien-Chih Chiu, Chun-Yen Liu, Ching-Fa Yao, Kang Fang* Apoptosis
2018-01 期刊論文 The impact of Bis(2-ethylhexyl) phthalate (DEHP) on cancer progression Chon-Kit Chou, Ya-Ting Yang, Ho-Chun Yang, Shih-Shin Liang, Tsu-Nai Wang, Po-Lin Kuo, Hui-Min David Wang, Eing-Mei Tsai*, Chien-Chih Chiu* Archivum Immunologiae et Therapiae Experimentalis
2017-08 期刊論文 Coral-Derived Natural Marine Compound GB9 Impairs Vascular Development in Zebrafish Yi-Chun Song, Bao-Jueng Wu, Chien-Chih Chiu, Chun-Lin Chen, Jun-Qing Zhou , Shuo-Rong Liang, Chang-Yih Duh, Ping-Jyun Sung, Zhi-Hong Wen, Chang-Yi Wu International Journal of Molecular Sciences
2017-08 期刊論文 The Potential Role of Krüppel-Like Zinc Finger Protein Glis3 in Genetic Diseases and Cancers Chon-Kit Chou,Chin-Ju Tang,Han-Lin Chou,Chun-Yen Liu,Ming-Chong Ng,Yu-Ting Chang,Shyng-Shiou F. Yuan,Eing-Mei Tsai,Chien-Chih Chiu* Archivum Immunologiae et Therapiae Experimentalis
2017-06 期刊論文 A Quinone-Containing Compound Enhances Camptothecin-Induced Apoptosis of Lung Cancer Through Modulating Endogenous ROS and ERK Signaling. Chou HL, Fong Y, Wei CK, Tsai EM, Chen JY, Chang WT, Wu CY, Huang HW, Chien-Chih Chiu*. Archivum Immunologiae et Therapia Experimentalis.
2017-05 期刊論文 9-bis[2-(pyrrolidin-1-yl)ethoxy]-6-{4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}-11H-indeno[1, 2-c]quinolin-11-one (BPIQ), A Quinoline Derivative Inhibits Human Hepatocellular Carcinoma Cells by Inducing ER Stress and Apoptosis Wen-Tsan Chang, Yao Fong, Shih-Chang Chuang, Chon-Kit Chou, Han-Lin Chou , Chun-Feng Yang, Chih-Hua Tseng, Yeh-Long Chen* and Chien-Chih Chiu* Anti-Cancer Agents in Medicinal Chemistry
2017-05 期刊論文 A 4-Phenoxyphenol Derivative Exerts Inhibitory Effects on Human Hepatocellular Carcinoma Cells through Regulating Autophagy and Apoptosis Accompanied by Downregulating α-Tubulin Expression Wen-Tsan Chang, Wangta Liu, Yi-Han Chiu, Bing-Hung Chen, Shih-Chang Chuang , Yen-Chun Chen, Yun-Tzh Hsu, Mei-Jei Lu, Shean-Jaw Chiou, Chon-Kit Chou and Chien-Chih Chiu* Molecules
2017-04 期刊論文 Fine-tune regulation of carboxypeptidase N1 controls vascular patterning during zebrafish development Ting-Yun Wu, Yi-Shan Wang, Yi-Chun Song, Zih-Ying Chen, Yi-Ting Chen, Chien-chih Chiu, Chang-Yi Wu Scientific Reports
2017-03 期刊論文 Dual roles of extracellular signal-regulated kinase (ERK) in quinoline compound BPIQ-induced apoptosis and anti-migration of human non-small cell lung cancer cells. Fong Y, Wu CY, Chang KF, Chen BH, Chou WJ, Tseng CH, Chen YC, Wang HD, Chen YL, Chien-Chih Chiu* Cancer Cell International
2017-03 期刊論文 PrdxI encode peroxiredoxin is important for vascular development in zebrafish Huang PC*, Chien-Chih Chiu*, Chang HW*, Wang YS, Hsiu HH, Song YC, Wen ZH, Tai MH and Wu CY. PrdxI encode peroxiredoxin is important for vascular development in zebrafish (Contributed equally) FEBS Letters
2017-03 期刊論文 The Transgenic Zebrafish Display Fluorescence Reflecting the Expressional Dynamics of Dihydrofolate Reductase Zebrafish Chang Wen-Ni, Chi Wan-Yu, Kao Tseng-Ting, Tsai Jen-Ning, Liu Wangta, Liang Shih-Shin, Chiu Chien-Chih, Chen Bing-Hung and Fu Tzu-Fun. Zebrafish
2017-02 期刊論文 The regulations of deubiquitinase USP15 and its pathophysiological mechanisms in diseases Chon-Kit Chou, Yu-Ting Chang, Michal Korinek, Yei-Tsung Chen, Ya-Ting Yang, Steve Leu, I-Ling Lin, Chin-Ju Tang, Chien-Chih Chiu* International Journal of Molecular Sciences
2016-12 期刊論文 An XIST-related small RNA regulates KRAS G-quadruplex formation beyond X-inactivation Chang YC, Chien-Chih Chiu, Yuo CY, Chan WL, Chang YS5, Chang WH, Wu SM, Chou HL, Liu TC, Lu CY, Yang WK, Chang JG* Oncotarget
2016-11 期刊論文 Sperm quality and DNA integrity of coke oven workers exposed to polycyclic aromatic hydrocarbons. Jeng HA, Pan CH, Chao MR, Chien-Chih Chiu, Zhou G, Chou CK, Lin WY. Int J Occup Med Environ Health.
2016-10 期刊論文 An Acetamide Derivative as a Camptothecin Sensitizer for Human Non-Small-Cell Lung Cancer Cells through Increased Oxidative Stress and JNK Activation Chou HL, Fong Y, Lin HH, Tsai EM, Chen JY, Chang WT, Wu CY, David Wang HM, Huang HW*, Chien-Chih Chiu*. Oxidative Medicine and Cellular Longevity
2016-10 期刊論文 Cytotoxicity of 11-epi- Sinulariolide Acetate Isolated from Cultured Soft Corals on HA22T Cells through the Endoplasmic Reticulum Stress Pathway and Mitochondrial Dysfunction.  Jen-Jie Lin, Robert Y. L. Wang, Jiing-Chuan Chen, Chien-Chih Chiu, Ming-Hui Liao* and Yu-Jen Wu*. International Journal of Molecular Sciences
2016-10 期刊論文 The inhibitory effect of trans-Ferulic acid on proliferation and migration of human lung cancer cells accompanied with increased endogenous ROS and β-catenin instability Yao Fong, Chia-Chun Tang, Huei-Ting Hu, Hsin-Yu Fang, Bing-Hung Chen, Chang-Yi Wu, Shyng-Shiou Yuan, Hui-Min David Wang, Yen-Chun Chen, Yen-Ni Teng, Chien-Chih Chiu* Chinese Medicine
2016-08 期刊論文 A novel role for β2-microglobulin: a precursor of antibacterial chemokine in respiratory epithelial cells Shean-Jaw Chiou*, Chan-Chi Wang, Yan-Shen Tseng, Yen-Jung Lee, Shih-Chieh Chen, Chi-Hsien Chou, Lea-Yea Chuang, Yi-Ren Hong, Chi-Yu Lu, Chien-Chih Chiu, Michel Chignard* Scientific Reports
2016-05 期刊論文 Bio-functional activities of Equisetum ramosissimum extract: protective effects against oxidation, melanoma and melanogenesis Pin-Hui Li, Yu-Pin Chiu, Chieh-Chih Shih, Zhi Hong Wen, Laura Kaodichi Ibeto, Shu-Hung Huang, Chien-Chih Chiu, Yaw-Nan Chang, Hui-Min Wang, Dik-Lung Ma, and Chung-Hang Leung Oxidative Medicine and Cellular Longevity
2016-04 期刊論文 Quinoline-Based Compound BPIQ Exerts Anti-Proliferative Effects on Human Retinoblastoma Cells via Modulating Intracellular Reactive Oxygen Species. Kai-Chun Cheng, Chun-Tzu Hung, Kuo-Jen Chen, Wen-Chuan Wu, Jau-Ling Suen, Cheng-Hsien Chang, Chi-Yu Lu, Chih-Hua Tseng, Yeh-Long Chen, Chien-Chih Chiu* Archivum immunologiae et therapiae experimentalis
2016-03 研討會論文 TFPP, a quinone compound enhances camptothecin-induced anti-human lung cancer NSCLC cells through blocking ERK activity and reducing the threshold of ROS-induced apoptosis (#P410) Han-Lin Chou, Hurng-Wern Huang, Chien-Chih Chiu*
2016-02 期刊論文 Reductive amination-assisted quantitation of tamoxifen and its metabolites by liquid phase chromatography tandem mass spectrometry. Liang SS, Wang TN, Chien-Chih Chiu, Kuo PL, Huang MF, Liu MC, Tsai EM. Journal of Chromatography A
2016-01 期刊論文 A novel cell-penetrating peptide suppresses breast tumorigenesis by inhibiting β-catenin/LEF-1 signaling. Hsieh TH, Hsu CY, Tsai CF, Chien-Chih Chiu, Liang SS, Wang TN, Kuo PL, Long CY, Tsai EM. Scientific Reports
2016-01 期刊論文 Discovery of Indeno[1,2-b]quinoxaline Derivatives as Potential Anticancer Agents Chih-Hua Tseng, You-Ren Chen, Cherng-Chyi Tzeng, Wangta Liu, Chon-Kit Chou, Chien-Chih Chiu*, Yeh-Long Chen* (*Corresponding authors) European Journal of Medicinal Chemistry
2016-01 期刊論文 Distinct CPT-induced deaths in lung cancer cells caused by clathrin-mediated internalization of CP micelles Liu YS, Cheng RY, Lo YL, Hsu C, Chen SH, Chien-Chih Chiu*, Wang LF*. (*Corresponding authors) Nanoscale
2015-12 期刊論文 7-Hydroxydehydronuciferine induces human melanoma death via triggering autophagy and apoptosis. Wu, Pei-Fang; Chien-Chih Chiu; Chen, Chung-Yi. Wang, Hui-Min. Experimental Dermatology
2015-12 期刊論文 BPIQ, a novel synthetic quinoline derivative, inhibits growth and induces mitochondrial apoptosis of lung cancer cells in vitro and in zebrafish xenograft model Chien-Chih Chiu*, Kuo-Feng Chang, Bing-Hung Chen, Han-Lin Chou, Chih-Hua Tseng, Yao Fong, Tzu-Fun Fu, Hsueh-Wei Chang, Chang-Yi Wu, Eing-Mei Tsai, Shinne-Ren Lin and Yeh-Long Chen* (*Corresponding authors) BMC Cancer
2015-12 期刊論文 Curcumin Suppresses Phthalate-Induced Metastasis and the Proportion of Cancer Stem Cell (CSC)-like Cells via the Inhibition of AhR/ERK/SK1 Signaling in Hepatocellular Carcinoma Cheng-Fang Tsai, Tsung-Hua Hsieh, Jau-Nan Lee, Chia-Yi Hsu, Yu-Chih Wang, Kung-Kai Kuo, Hua-Lin Wu, Chien-Chih Chiu, Eing-Mei Tsai*, and Po-Lin Kuo* Journal of Agricultural and Food Chemistry
2015-12 研討會論文 A quinone derivative enhances camptothecin-induced apoptosis of non-small cell lung cancer cells through modulating endogenous reactive oxygen species (#P22) Chi-Ku Wei, Han-Lin Chou, Chien-Chih Chiu*
2015-11 期刊論文 An indolylquinoline derivative promotes apoptosis in human lung cancer cells by impairing mitochondrial functions. Chun-Yen Liu, Pei-Tsen Wu, Chun-Li Su, Jing-Ping Wang, Chien-Chih Chiu, Po-Wei Fan, Ching-Fa Yao, Chang-Hung Hsieh, Kang Fang Apoptosis
2015-09 期刊論文 Reactive oxygen species mediate Terbufos-induced apoptosis in mouse testicular cell lines via the modulation of cell cycle and pro-apoptotic proteins. Hung JH, Chen CY, Omar HA, Huang KY, Tsao CC, Chien-Chih Chiu, Chen YL, Chen PH, Teng YN. Environmental Toxicology
2015-08 期刊論文 4-(Phenylsulfanyl)butan-2-One Suppresses Melanin Synthesis and Melanosome Maturation In Vitro and In Vivo. Shing-Yi Sean Wu, Hui-Min David Wang, Yi-Shan Wen, Wangta Liu, Pin-Hui Li, Chien-Chih Chiu, Pei-Chin Chen, Chiung-Yao Huang Jyh-Horng Sheu, Zhi-Hong Wen. International Journal of Molecular Sciences
2015-08 期刊論文 Folic Acid Linked Chondroitin Sulfate-Polyethyleneimine Copolymer Based Gene Delivery System Yu-Lun Lo; Pei-Chi Lo; Chien-Chih Chiu; Li-Fang Wang Journal of Biomedical Nanotechnology
2015-07 期刊論文 BubR1 Acts as a Promoter in Cellular Motility of Human Oral Squamous Cancer Cells through Regulating MMP-2 and MMP-9. Chon-Kit Chou, Chang-Yi Wu, Jeff Yi-Fu Chen, Ming‐Chong Ng, Hui-Min David Wang, Jen-Hao Chen, Shyng-Shiou F Yuan, Eing-Mei Tsai, Jan-Gowth Chang*, Chien-Chih Chiu* International Journal of Molecular Sciences
2015-06 研討會論文 The role of nuclear RNA export Factor (NXF2) in regulating motility and growth of hepatocellular carcinoma cells (#CSCI2015_0171) Chien-Chih Chiu, C.Y. Yuo, K.T. Yeh, Y.S. Chang,  S.Y. Hung, Y.L. Chang, H.L. Chou J.G. Chang
2015-05 期刊論文 Chondroitin sulfate-polyethylenimine copolymer-coated superparamagnetic iron oxide nanoparticles as an efficient magneto-gene carrier for microRNA-encoding plasmid DNA delivery. Lo YL, Chou HL, Liao ZX, Huang SJ, Ke JH, Liu YS, Chien-Chih Chiu, Wang LF* Nanoscale
2015-04 期刊論文 Polygonum cuspidatum extracts as bioactive antioxidaion, anti-tyrosinase, immune stimulation and anticancer agents. Lee, C. C., Chen, Y. T., Chien-Chih Chiu, Liao, W. T., Liu, Y. C., & Wang, H. M. D. Journal of Bioscience and Bioengineering
2015-01 期刊論文 Discovery of 2-[2-(5-nitrofuran-2-yl)vinyl]quinoline derivatives as a novel type of antimetastatic agents. Tseng, C. H., Tzeng, C. C., Chien-Chih Chiu, Hsu, C. Y., Chou, C. K., & Chen, Y. L. Bioorganic & Medicinal Chemistry
2014-12 研討會論文 Synthetic quinone exerts anti-growth in zebrafish hosting lung cancer xenograft through Akt and ATM/ATR pathways. Mei-Jei Lu, Chang-Yi Wu, Wang-Ta Liu, Chien-Chih Chiu*
2014-10 期刊論文 Brefeldin A Reduces Anchorage-Independent Survival, Cancer Stem Cell Potential and Migration of MDA-MB-231 Human Breast Cancer Cells Chao-Neng Tseng, Yi-Ren Hong, Hsueh-Wei Chang, Tsai-Jung Yu, Ting-Wei Hung, Ming-Feng Hou, Shyng-Shiou F. Yuan , Chung-Lung Cho, Chien-Tsung Liu, Chien-Chih Chiu and Chih-Jen Huang Molecules
2014-09 期刊論文 Polygonum cuspidatum extracts as bioactive antioxidaion, anti-tyrosinase, immune stimulation and anticancer agents. Chih-Chen Lee, Yen-Ting Chen, Chien-Chih Chiu, Su-Shin Lee, Wei-Ting Liao, Kuo-Chuan Huang, Kuo-Chen Cheng *, Hui-Min Wang * Journal of Bioscience and Bioengineering
2014-07 期刊論文 Complex molecular features of gemcitabine­resistant human urothelial carcinoma sublines Yu-Ting Kao, Wei-Chi Hsu, Huei-Ting Hu, Shih-Hsien Hsu, Chang-Shen Lin, Chien-Chih Chiu, Chi-Yu Lu, Tzyh-Chyuan Hour, Yeong-Shiau Pu, A-Mei Huang The Kaohsiung Journal of Medical Sciences
2014-07 期刊論文 Correlation between leucine rich domain and the stability of LRWD1 protein in human NT2/D1 cells. Yung-Chieh Tsai, Yen-Ni Teng, Jui-Hsiang Hung, Chien-Hsing Wu, Yu-Ting Kuo, Pao-Lin Kuo, Chien-Chih Chiu, Bin Huang Journal of Biomedical Science
2014-07 期刊論文 Nnuclear receptor subfamily 2 group F member 1A (Nr2f1a) is required for vascular development in zebrafish Bao-Jueng Wu#, Chien-Chih Chiu#, Chun-Lin Chen, Wen-Der Wang, Jia-Hong Wang, Zhi-Hong Wen, Wangta Liu, and Chang-Yi Wu. # contributed equally. PLoS ONE
2014-06 期刊論文 The anti-proliferative and apoptotic effects of sirtinol, a sirtuin inhibitor on human lung cancer cells by modulating Akt/β-catenin-Foxo3A axis Yao Fong, Ying-Chieh Lin, Chang-Yi Wu, Hui-Min David Wang, Li-Li Lin, Han Lin Chou, Yen-Ni Teng, Shyng-Shiou F Yuan, and Chien-Chih Chiu* The Scientific World Journal
2014-05 期刊論文 Cardiotoxin III suppresses hepatocyte growth factor-stimulated migration and invasion of MDA-MB-231 cells. Pei-Chien Tsai, Chiao-Lun Chu, Chien-Chih Chiu, Long-Sen Chang, Shinne-Ren Lin Cell Biochemistry and Function
2014-05 期刊論文 Progesterone Increases Apoptosis and Inversely Decreases Autophagy in Human Hepatoma HA22T/VGH Cells Treated with Epirubicin Wen-Tsan Chang, Hsiao-Ling Cheng, Bau-Shan Hsieh, Chien-Chih Chiu, King-Teh Lee, Kee-Lung Chang The Scientific World Journal
2014-05 期刊論文 Synthesis and antiproliferative evaluation of 9-methoxy-6-(piperazin-1-yl)-11H-indeno[1,2-c]quinoline-11-one derivatives. Part 4 Chih-Hua Tseng, Cherng-Chyi Tzeng, Chien-Chih Chiu, Chiao-Li Yang, Pei-Jung Lu, Chon-Kit Chou, Chun-Yen Liue and Yeh-Long Chen MedChemComm
2014-05 研討會論文 A naphthoquinone analogue exerts an anti-proliferative effect on human lung cancer cells through inducing DNA damage and ROS production. Pin-Hsuan Wu, Chang-Yi Wu, Yeh-Long Chen, Chien-Chih Chiu*
2014-04 期刊論文 Preparing Chondroitin Sulfate-g-Poly(ε-Caprolactone) Copolymers as a CD44-Targeted Vehicle for Enhanced Intracellular Uptake Yu-Sheng Liu, Chien-Chih Chiu, Hsuan-Ying Chen, Su-Hwei Chen, Li-Fang Wang Molecular Pharmaceutics
2014-01 期刊論文 The antiproliferative effect of C2-ceramide on lung cancer cells through apoptosis by inhibiting Akt and NFkB I-Ling Lin, Han-Lin Chou, Jin-Ching Lee, Feng-Wei Chen, Yao Fong, Wei-Chiao Chang, H.-W. Huang, Chang-Yi Wu, Wen-Tsan Chang, Hui-Min Wang and Chien-Chih Chiu* Cancer Cell International
2013-12 研討會論文 Chloroquine synergistically promotes C2-ceramide induced apoptosis of non-small cell lung cancer cells via inhibiting sirt1 expression. Han-Lin Chou, Hurng-Wern Huang, Chien-Chih Chiu*
2013-11 期刊論文 Involvement of p38 mitogen-activated protein kinase in acquired gemcitabine-resistant human urothelial carcinoma sublines Yu-Ting Kao, Wei-Chi Hsu, Huei-Ting Hu, Shih-Hsien Hsu, Chang-Shen Lin, Chien-Chih Chiu, Chi-Yu Lu, Tzyh-Chyuan Hour, Yeong-Shiau Pu, A-Mei Huang The Kaohsiung Journal of Medical Sciences
2013-09 期刊論文 Alpinia oxyphylla Miq. bioactive extracts from supercritical fluid carbon dioxide extraction. Chih-Chen Lee, Chien-Chih Chiu, Wei-Ting Liao, Pei-Fang Wu, Yi-Ting Chou, Kuo-Chuan Huang, Yen-Ting Chen, Zhi-Hong Wen and Hui-Min Wang*. Biochemical Engineering Journal.
2013-09 期刊論文 Reduction of RNA A-to-I editing in Drosophila acclimated to heat shock. Joel Stocker, Hurng-Wern Huang, Hong-Ming Wang, Hsueh-Wei Chang, Chien-Chih Chiu, Chung-Lung Cho, and Chao-Neng Tseng. Kaohsiung Medical Science
2013-08 期刊論文 Brefeldin A Effectively Inhibits Cancer Stem Cell Properties and MMP-9 Activity in Human Colorectal Cancer Colo 205 cells. Chao-Neng Tseng, Chien-Fu Huang, Chung-Lung Cho, Hsueh-Wei Chang, Chao-Wei Huang, Chien-Chih Chiu*, and Yung-Fu Chang*. Molecules
2013-08 期刊論文 Brefeldin A inhibits Cancer Stem Cell Properties in Human Lung Cancer Cells. Chao-Neng Tseng, Chung-Lung Cho, Tzan-Wen Chen, Chien-Chih Chiu, Hsueh-Wei Chang, Fang-Rong Chang, Yung-Fu Chang. Current Signal Transduction Therapy.
2013-08 期刊論文 Feruloyl-L-arabinose attenuates migration, invasion and production of reactive oxygen species in H1299 lung cancer cells. Hsin-Yu Fang, Hui-Min Wang, Kuo-Feng Chang, Huei-Ting Hu, Lian-Je Hwang, Tzu-Fun Fu, Yin-Chieh Lin, Wei-Chiao Chang, Tsu-Pei Chiu, Zhi-Hong Wen , Chien-Chih Chiu*, Bing-Hung Chen* Food and Chemical Toxicology.
2013-08 期刊論文 Inhibition of Src activation with Cardiotoxin III blocks migration and invasion of MDA-MB-231 cells. Pei-Chien Tsai, Chiao-Lun Chu, Chien-Chih Chiu, Long-Sen Chang, Shinne-Ren Lin. Toxicon.
2013-08 期刊論文 Magnolol induces apoptosis via caspase-independent pathways in non-small cell lung cancer cells. Tsai JR, Chong IW, Chen YH, Hwang JJ, Yin WH, Chen HL, Chou SH, Chien-Chih Chiu, Liu PL. Archives of pharmacal research
2013-08 期刊論文 Teroxirone inhibited growth of human non-small cell lung cancer cells by activating p53. Jing-Ping Wang, Kai-Han Lin, Chun-Yen Liu, Ya-Chu Yu, Chien-Chih Chiu, Chun-Li Su, Kwun-Min Chen, Kang Fang. Toxicology and Applied Pharmacology.
2013-08 研討會論文 Anti-allergic activity of grape seed extract (GSE) on RBL-2H3 mast cells. Chien Chih, Chiu and Bing-Hung Chen*
2013-07 期刊論文 Proteomic investigation of the sinulariolide-treated melanoma cells A375: effects on the cell apoptosis through mitochondrial-related pathway and activation of caspase cascade (@ contributed equally). Hsing-Hui Li, Jui-Hsin Su Su@, Chien-Chih, Chiu@, Jen-Jie Lin, Zih-Yan Yang, Wen-Ing Hwang, Yu-Kuei Chen, Yu-Hsuan Lo, Yu-Jen Wu*. Marine Drugs
2013-07 研討會論文 The effect of Akt-targeting compounds on proliferation and apoptosis of lung cancer cells in zebrafish xenografts. Mei-Jei Lu and Chien-Chih Chiu*
2013-06 期刊論文 Calreticulin, an endoplasmic reticulum-resident protein, is highly expressed and essential for cell proliferation and migration in oral squamous cell carcinoma. Wei-Fan Chiang, Tzer-Zen Hwang, Tzyh-Chyuan Hour, Lee-Hsin Wang, Chien-Chih Chiu, Hau-Ren Chen, Yu-Jen Wu, Chih-Chun Wang, Ling-Feng Wang, Chen-Yu Chien, Jen-Hao Chen, Chao-Tien Hsu, Jeff Yi-Fu Chen. Oral Oncology.
2013-06 期刊論文 Enhancements on skin cell proliferations and migrations via 6-dehydrogingerdione. Chen, Chung-Yi; Chiu, Chien-Chih; Wu, Chi-Peng; Chou, Yi-Ting; Wang, Hui-Min. Journal of Agricultural and Food Chemistry.
2013-06 期刊論文 Transcribed pseudogene ψPPM1K generates endogenous siRNA to suppress oncogenic cell growth in hepatocellular carcinoma. Wen ling Chan, Chung Yee Yuo, Wen uang Yang, Shih Huang, Ya Ian Chang, Chien Chih Chiu, Kun Tu Yeh, Hsien Huang, Jan Jowth Chang. Nucleic Acid Research.
2013-05 期刊論文 Golden berry-derived 4β-hydroxywithanolide E for selectively killing oral cancer cells by generating ROS, DNA damage, and apoptotic pathways. Chien-Chih Chiu, Jo-Wen Huang, Fang-Rong Chang, Kuang-Jing Huang, Hsuan-Min Huang, Hurng-Wern Huang, Chon-Kit Chou, Yang-Chang Wu, Hsueh-Wei Chang*. PLoS ONE.
2013-04 期刊論文 Cardiotoxin III Inhibits Proliferation and Migration of Oral Cancer Cells through MAPK and MMP Signaling. Ching-Yu Yen, Shih-Shin Liang, Lo-Yi Han, Han-Lin Chou, Chon-Kit Chou, Shinne-Ren Lin*, Chien-Chih Chiu*. The Scientific World Journal.
2013-03 期刊論文 Lucidone Suppresses Hepatitis C Virus Replication by Nrf2-Mediated Heme Oxygenase-1 Induction. Wei-Chun Chen, Sheng-Yang Wang, Chien-Chih Chiu, Chin-Kai Tseng, Hui-Chun Wang, and Jin-Ching Lee. Antimicrobial Agents and Chemotherapy.
2013-03 期刊論文 Retinol-encapsulated water-soluble succinated chitosan nanoparticles for antioxidant applications. Shih-Jer Huang, Shou-Li Sun, Chien-Chih Chiu, Li-Fang Wang. Journal of Biomaterials Science, Polymer Edition
2013-02 期刊論文 Chemically Conjugating Polyethylenimine with Chondroitin Sulfate to Promote CD44-Mediated Endocytosis for Gene Delivery. Yu-Lun Lo, Kuo-Hsun Sung, Chien-Chih Chiu and Li-Fang Wang. Molecular Pharmaceutics
2012-05 期刊論文 Biological Properties of Acidic Cosmetic Water from Seawater Wei-Ting Liao, Tsi-Shu Huang, Chien-Chih Chiu, Jian-Liang Pan, Shih-Shin Liang,Bing-Hung Chen , Shi-Hui Chen, Po-Len Liu, Hui-Chun Wang, Zhi-Hong Wen,Hui-Min Wang* and Shu-Wen Hsiao* International Journal of Molecular Sciences
2012-04 期刊論文 Bio-Functional Constituents from the Stems of Liriodendron tulipifera Chien-Chih Chiu, Han-Lin Chou, Pei-Fang Wu, Hsin-Liang Chen, Hui-Min Wang*, Chung-Yi Chen* Molecules
2012-02 期刊論文 Anti-allergic activity of grape seed extract (GSE) on RBL-2H3 mast cells. Bing-Hung Chen*, Mei-Huei Hung, Jeff Yi-Fu Chen, Hsueh-Wei Chang, Meng-Lung Yu, Lei Wan, Fuu Jen Tsai, Tzu-Pin Wang, Tzu-Fun Fu, Chien-Chih Chiu*. Food Chemistry
2012-02 期刊論文 Proteomic investigation of anti-tumor activities exerted by sinularin against A2058 melanoma cells. Tzu-Rong Su, Jen-Jie Lin, Chien-Chih Chiu, Jeff Yi-Fu Chen, Jui-Hsin Su, Zhi-Jiao Cheng, Wen-Ing Hwang, Han Hsiang Huang§ and Yu-Jen Wu§. Electrophoresis
2011-10 期刊論文 Goniothalamin inhibits growth of human lung cancer cells through DNA damage, apoptosis and reduced migration ability. Chien-Chih Chiu, Po-Len Liu, Kuang-Jing Huang, Kuo-Feng Chang, Hui-Min Wang, Chon-Kit Chou, Jia-Shing Chen, Kang Fang, Yang-Chang Wu, Hsueh-Wei Chang. Journal of Agricultural and Food Chemistry
2011-08 期刊論文 Feruloyl-L-arabinose, a ferulic acid derivative extracted from Zizania latifolia, exerts an antimigration effect on human lung cancer cells via down-regulating endogenous reactive oxygen species Hsin-Yu Fang, Ph.D.; Chien-Chih Chiu, Ph.D.; Kuo-Feng Chang, M.S. ; Huei-Ting Hu, M.S.; Lian-Je Hwang, M.S.; Hui-Min Wang, Ph.D. ; Tzu-Fun Fu, Ph.D. ; Yin-Chieh Lin, M.S. ; Wei-Chiao Chang, Ph.D. ; Tsu-Pei Chiu, M.S. ; Bing-Hung Chen, Ph.D. Food and Chemical Toxicology
2011-06 期刊論文 Subamolide E from Cinnamomum subavenium induces sub-G1 cell cycle arrest, caspase-dependent apoptosis, and reduces migration ability of human melanoma cells. Hui-Min Wang, Chien-Chich Chiu, Pei-Fang Wu, Chung-Yi Chen* Journal of Agricultural and Food Chemistry
2011-05 期刊論文 Overexpression of Rho GDP-dissociation inhibitor alpha predicts poor survival in oral squamous cell carcinoma. Wei-Fan Chiang, Hsu-Chueh Ho, Hua-Yuan Chang, Chien-Chih Chiu, Yuh-Ling Chen, Tzyh-Chyuan Hour, Shu-Ju Chuang, Yu-Jen Wug, Hau-Ren Chen h, Jen-Hao Chen, Shyun-Yeu Liu, Chin-Li Lu, Jeff Yi-Fu Chen. Oral Oncology
2011-04 期刊論文 Characterization and enhancement of chondrogenesis in porous hyaluronic acid-modified scaffolds made of PLGA (75/25) blended with PEI-grafted PLGA (50/50) Chau-Zen Wang, Mei-Ling Ho, Wen-Cheng Chen, Chien-Chih Chiu, Yung-Li Hung, Chih-Kuang Wang, Shun-Cheng Wu. Materials Science and Engineerin: C
2011-02 期刊論文 Antitumor Efficacy of Doxorubicin Released from Crosslinked Nanoparticulate Chondroitin Sulfate/Chitosan Polyelectrolyte Complexes. Hun-Yu Tsai, Chien-Chih Chiu, Ping-Chih Lin, Su-Hwei Chen, Shih-Jer Huang, Li-Fang Wang*. Macromolecular Bioscience
2011-01 期刊論文 Anticancer Activity of Released Doxorubicin from a Folate-Mediated Polyelectrolyte Complex. Chiu CC, Lin YT, Sun SL, Sung KH, Wang LF*. Journal of Biomaterials Science
2011-01 期刊論文 CASP3 gene single nucleotide polymorphism (rs72689236) and Kawasaki disease in Taiwanese children. Kuo HC, Yu HR, Juo SH, Yang KD, Wang YS, Liang LD, Chen WC, Chang WP, Huang CF, Lee CP, Lin LY, Liu YC, Guo YC, Chien-Chih Chiu and Chang WC* Journal of Human Genetics
2010-11 期刊論文 San-Huang-Xie-Xin-Tang extract suppresses hepatitis C virus replication and virus-induced cyclooxygenase-2 expression J.-C. Lee,C.-k. Tseng,S.-F. Wu,F.-R. Chang,C.-C. Chiu and Y.-C. Wu Journal of Viral Hepatitis
2010-10 期刊論文 p38 MAPK is Involved in Ceramide Sensitizes Paclitaxel-induced Premature Senescence of Human Lung Cancer Cells Chi-Ching Huang, Bing Hung Chen, Wei-Yi Chen, and Ching-Chih Lee, Ya-Lan Huang, Chien-Chih Chiu* Life Sciences
2010-09 期刊論文 Obtusilactone A and (-)-sesamin induce apoptosis in human lung cancer cells via inhibiting mitochondrial Lon protease and activating DNA damage checkpoints Hui-Min Wang, Kuo-Chen Cheng, Shu-Wei Hsu, Hsi-An Chen, Cheng-Jung Lin, Wei-Cheng Fang, Tai-Feng Hsu, Chien-Chih Chiu, Hsueh-We Cancer Science
2010-07 期刊論文 Additive effects of C2-ceramide on Paclitaxel-induced premature senescence of human lung cancer cells. Chen JY, Hwang CC, Chen WY, Lee JC, Fu TF, Fang K, Chu YC, Huang YL, Lin JC, Tsai WH, Chang HW, Chen BH, Chiu CC*. Life Sciences
2010-07 期刊論文 Betel quid extract promotes oral cancer cell migration by activating a muscarinic M4 receptor-mediated signaling cascade involving SFKs and ERK1/2. Chiu CC, Chen BH, Hour TC, Chiang WF, Wu YJ, Chen CY, Chen HR, Chan PT, Liu SY, Chen JY. Biochemical and Biophysical Research Communications
2010-07 期刊論文 Decreased Expression of Thrombomodulin is Correlated with Tumor Cell Invasiveness and Poor Prognosis in Non-small Cell Lung Cancer. Liu PL, Tsai JR, Chiu CC, Hwang JJ, Chou SH, Wang CK, Wu SJ, Chen YL, Chen WC, Chen YH, Chong IW. Mol Carcinogenesis
2010-05 期刊論文 Identification of anti-lung cancer extract from Chlorella vulgaris C-C by antioxidant property using supercritical carbon dioxide extraction. Hui-Min Wang, Jian-Liang Pan, Chun-Yen Chen, Chien-Chich Chiu, Mu-Hoe Yang, Hsueh-Wei Chang, Jo-Shu Chang. Process Biochemistry
2010-05 期刊論文 Taiwan cobra cardiotoxin III inhibits Src kinase leading to apoptosis and cell cycle arrest of oral squamous cell carcinoma Ca9-22 cells. Chien CM, Chang SY, Lin KL, Chiu CC, Chang LS, Lin SR*. Toxicon
2010-03 期刊論文 p38 MAPK and NFκB pathways are involved in Naphtho[1,2-b] furan-4,5-dione induced anti-proliferation and apoptosis of human hepatoma cells Chien-Chih Chiu*, Chi-Jung Huang, Chen, Wan-Yu, Lo-Yi Han, Shinne-Ren Lin* Cancer Letters
2010-02 期刊論文 4β-hydroxywithanolide E from Physalis peruviana (golden berry) inhibits growth of human lung cancer cells through DNA damage, apoptosis and G2/M arrest Chien-Chih Chiu,Ching-Yu Yen, Fang-Rong Chang,You-Cheng Hseu, Hsin-Ling Yang, Alan Yueh-Luen Lee, Mi BMC cancer
2010-01 期刊論文 Contributions of active site residues to cofactor binding and catalysis of 3α-hydroxysteroid dehydrogenase/carbonyl reductase Yi-Hsun Chang, Chau-Zen Wang, Chien-Chih Chiu, Lea-Yea Chuang and Chi-Ching Hwang* Biochimica et Biophysica Acta (BBA) - Proteins & Proteomics
2009-10 期刊論文 Fern plant-derived protoapigenone leads to DNA damage, apoptosis and G2/M arrest in lung cancer cell line H1299 Chien-Chih Chiu,Hsueh-Wei Chang,Da-Wei Chuang,Fang-Rong Chang,Yu-Ching Chang,Yu-Shan Cheng, Ming-Tz DNA and Cell Biology
2009-08 期刊論文 Characterization and the enhancement of chondrogenesis in porous Chau-Zen Wang, Mei-Ling Ho, Wen-Cheng Chen, Chien-Chih Chiu, Yung-Li, Hung, Chih-Kuang Wang*, Shun-Cheng Wu Acta Biomaterialia
2009-03 期刊論文 Effects of cardiotoxin III on NFκB function, proliferation and apoptosis in human breast MCF-7 cancer cells Chien-Chih Chiu, Kuei-Li Lin, Ching-Ming Chien, Long-Sen Chang, Shinne-Ren Lin* Oncology Research